Vitamin B Complex and Zinc are Essential for Life

Thiamine (Vitamin B1) is a catalyst involved in many cellular metabolic activities of the body. It also involves initiation of nerve impulse propagation of the nervous system.^[2,10]

Pyridoxine (Vitamin B6) is important in protein, fat and carbohydrate metabolism and the creation of red blood cells and neurotransmitters.(10) Plays a role in preventing eye diseases, especially vision loss. Pyridoxine improves brain function and mood regulation. It also lowers the risk of developing certain types of cancer. play a role in improving brain function.^[15]

Cyanocobalamin (Vitamin B12) important for growth, cell reproduction and energy, healthy red blood cell formation and nerve cell maintenance.^[10]

Lysine is vital for the formation of collagen, an essential protein that affects wound repair. Lysine appears to improvebones and also play a part in controlling where calcium is transported in the body.^[8]

Zinc is an essential trace element with key roles in growth, tissue repair and wound healing, intestinal mucosal integrity, synthesis of testicular hormones, and the immune response. Zinc is vital to normal anabolic activity including growth, tissue integrity, and wound healing.^[1]

Vitamin B1 Deficiency will present as Beri-Beri. There are 2 types of beriberi. Wet Beri-Beri is characterized with high output Heart failure, Right ventricle hypertrophy, Tachycardia (fast heart rate) or Bradycardia (slow heart rate), difficulty of breathing (Dyspnea) or respiratory distress, edema in the lower extremities, oliguria (low urine output) and lactic acidosis. Dry Beri-Beri have peripheral neuropathy, muscle weakness, gait ataxia, paresthesia and in severe form Wernicke’s Encephalopathy. Wernicke’s encephalopathy leads to ophthalmoplegia, ataxia, changes in mental state if left untreated it will lead to comatose state and death.

Vitamin B6 Deficiency have primary manifestations such as dermatitis, glossitis, and microcytic anemia. It also has other manifestation which are nonspecific stomatitis, glossitis, cheilosis, irritability, confusion, and depression, and possibly peripheral neuropathy . In severe deficiency seborrheic dermatitis, microcytic anemia, and seizures are the common presentation.

Vitamin B12 Deficiency have 4 stages and stages 1 have decreased levels of vitamin B12 in the blood. In Stage 2 the low levels of vitamin B12 in the cells with metabolic abnormalities in the body. Stage 3 will present with neurological and psychological symptoms like anxiety, confusion, problems with balance, and others. During stage 4 the blood picture is macrocytic anemia (very large red blood cell) which easily lyse. Vitamin B12 deficiency can be slow to develop, causing symptoms to appear gradually and intensify over time. It can also come on relatively quickly. Given the array of symptoms a vitamin B12 deficiency can cause, the condition can be overlooked or confused with something else. Vitamin B12 deficiency symptoms are strange sensations, numbness, or tingling in the hands, legs, or feet; difficulty walking (staggering, balance problems); anemia; a swollen, inflamed tongue; difficulty thinking and reasoning (cognitive difficulties), or memory loss; weakness and fatigue.

Lysine HCL Deficiency is characterized with reduce growth and bone metabolism and hence making children stunted and prone to fractures with easy fatigability. Other manifestation includes defective connective tissues, impaired fatty acid metabolism, anaemia, and systemic protein-energy deficiency. In contrast, an overabundance of lysine, caused by ineffective catabolism, can cause severe neurological disorders.

Zinc Deficiency have most common symptoms like appetite loss, slower than expected growth, poor immune system function. In severe zinc deficiency can cause even more concerning symptoms which are delayed sexual maturity, diarrhea, eye and skin lesions, feeling lethargic, funny-taste sensations, hair loss, poor wound healing, unexplained weight loss. Men and boys with zinc deficiency may experience impotence and hypogonadism, which is when a male’s body does not produce enough testosterone.